Bone marrow-on-a-chip provides new research directions for Shwachman-Diamond syndrome

Updated: Jan 16

Boston Children's Hospital's Discoveries Blog features this exciting story about SDS research. Read the full story, here.

In a research paper published January 27 in Nature Biomedical Engineering, researchers describe how weakened bone marrow from SDS patients performed in a new research tool, known as the organ-on-a-chip (Organ Chip). They hope it will provide a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome (SDS), and help develop new treatments one day.

“This model can be used for biological studies and for drug screening,” says Dr. Shimamura. “In my lab, we have identified some potential therapeutic targets for treating SDS that we hope to test with the new bone marrow chip.”

Read the whole story, here.

The scientific research paper is available, here.

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